Professor Tom LEYSSENS

External Expert - Louvain-la-Neuve (UCL), Belgium

Project Roles: Member Supervisory Board

Background

Prof. Tom Leyssens performed his PhD in theoretical chemistry at the UCL (Louvain-la-Neuve, Belgium). He then left for a short post-doctoral research stay at the Max-Planck Institute in Mulheim, a position he left to take up a Team Leader position at UCB Pharma (Braine l'Alleud Belgium). During his three years in industry, Tom Leyssens was responsible for the Development and Upscaling of robust Processes, specifically  targetting crystallization processes of pharmaceutically active compounds. He took his passion for crystallization of pharmaceutical compounds with him, when he took up an acadamic position in 2009 at the UCL (Belgium), where he is currently still running a lab in crystallization and crystal engineering.

Research Interests

Tom Leyssens' research mainly concerns multi-component crystalline systems, and the development of applications hereof. His current interest mainly lies in co-crystal systems, and their use. In this context, he is interested in using co-crystallization as a separation tool (chiral resolution, purification). From a crystal engineering point of view, his group is currently also inverstigating how co-crystallization can impact the photo- and thermochromic behavior.

Selected Publications

Matheys C., Tumanova N. , Leyssens T., Myerson S.A. 2016 Cryst. Growth Des., 16, 5549-5553.'Magnetic Levitation as a tool for separation: separating cocrystals from crystalline phases of individual compounds.'                                                            
Carletta A., Buol X. , Leyssens T., Champagne B., Wouters J. 2016 J. Phys. Chem. C, 120(18), 10001-10008. 'Polymorphic and Isomorphic Cocrystals of a N-Salicylidene-3-aminopyridine with Dicarboxylic Acids: Tuning of Solid-State Photo- and Thermochromism'                                        
Leyssens T., Tumanova N., Robeyns K., Candoni N., Veesler S. 2014 CrystEngComm, 16(41), 9603-9611.'Solution cocrystallization, an effective tool to explore the variety of cocrystal systems: caffeine/dicarboxylic acid cocrystals'                          
Springuel G., Collard L.,  Leyssens T. 2013 CrystEngComm., 15(39), 7951-7958.'Ternary and quaternary phase diagrams: key tools for chiral resolution through solution cocrystallization.'                
Springuel G., Leyssens T. Cryst. Growth. Des. 2012, 12(7), 3374-3378.'Innovative Chiral resolution using enantio-specific co-crystallization in solution. '

Contact details

tom.leyssens@uclouvain.be
+32 10 47 28 11
www.uclouvain.be/leyssens-group